Cysteine Protease Cathepsins in Atherosclerosis and Abdominal Aortic Aneurysm
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چکیده
منابع مشابه
Cysteine Protease Cathepsins in Atherosclerotic Cardiovascular Diseases
Atherosclerotic cardiovascular disease (ASCVD) is an inflammatory disease characterized by extensive arterial wall matrix protein degradation. Cysteine protease cathepsins play a pivotal role in extracellular matrix (ECM) remodeling and have been implicated in the development and progression of atherosclerosis-based cardiovascular diseases. An imbalance in expression between cathepsins (such as...
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متن کاملBrief Review Cysteine Protease Cathepsins in Atherosclerosis-Based Vascular Disease and Its Complications
Atherosclerosis-based vascular disease is an inflammatory disease characterized by extensive remodeling of the extracellular matrix architecture of the arterial wall. Although matrix metalloproteinases and serine proteases participate in these pathological events, the discovery of cysteine protease cathepsins, such as cathepsins K, S, L, and B, and cystatin C, and their tissue distribution has ...
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Atherosclerosis-based vascular disease is an inflammatory disease characterized by extensive remodeling of the extracellular matrix architecture of the arterial wall. Although matrix metalloproteinases and serine proteases participate in these pathological events, the discovery of cysteine protease cathepsins, such as cathepsins K, S, L, and B, and cystatin C, and their tissue distribution has ...
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AIMS The role of cardiovascular risk factors and atherosclerosis in the aetiology of abdominal aortic aneurysms is not well understood. The aim of this study was to determine the association between atherosclerosis and aortic aneurysm in the general population and the extent to which cardiovascular risk factors might increase the risk of aneurysm independently of an effect on atherosclerotic di...
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ژورنال
عنوان ژورنال: Clinical Reviews in Bone and Mineral Metabolism
سال: 2011
ISSN: 1534-8644,1559-0119
DOI: 10.1007/s12018-011-9098-2